I *think* putting your phone number on this list helps a bit.
https://www.ftc.gov/faq/consumer-protection/list-number-national-do-not-call-registry
In any event, it at least gives you the ability (if you want to) to talk to the human on the junk calls and tell them that their call is not just annoying, but actually illegal!
Sadly, it doesn't ban political fund raising calls 
What really helps reduce the number of junk calls is to let all your calls go through to voicemail and only "pick up" if you recognize the voice of the caller. After a while your number gets tagged as "doesn't answer" and the volume of junk calls goes down.
Though I have to admit, I really enjoy the spammers that call trying to tell me my computer is infected. They're almost always following a script that assumes you have a Windows machine (I have a lot of Macs) and assume that you have only one computer (I've got, um, several). I try and get them to tell me the internet address of the machine they believe is infected and they get really confused. Sadly, they've stopped calling too
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