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BumRushDaShow

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39. One of the points of mRNA is that it doesn't NEED eggs!

Thu May 8, 2025, 05:39 AM

May 8

The whole "egg" thing, which has been how the more traditional vaccines are cultured, was one of the things that this tech tried to be an alternative to. By not requiring the eggs, the mRNA vaccines can be manufactured much faster and the actual manufacture can occur later in the year ahead of the fall season, allowing more time to determine what variant is circulating the most as the one selected to go with. Moderna and Pfizer have been working on mRNA flu shots for a few years.

J Virol. 2022 Dec 19;97(1):e01723-22. doi: 10.1128/jvi.01723-22

Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation

(snip)

ABSTRACT

Most human influenza vaccine antigens are produced in fertilized chicken eggs. Recent H3N2 egg-based vaccine antigens have limited effectiveness, partially due to egg-adaptive substitutions that alter the antigenicity of the hemagglutinin (HA) protein. The nucleoside-modified mRNA encapsulated in lipid nanoparticles (mRNA-LNP) vaccine platform is a promising alternative for egg-based influenza vaccines because mRNA-LNP-derived antigens are not subject to adaptive pressures that arise during the production of antigens in chicken eggs.

(snip)

ALSO REFERENCE - https://www.democraticunderground.com/10143254580

Moderna trial info - https://trials.modernatx.com/study/?id=mRNA-1083-P301

NIH publication - mRNA-based seasonal influenza and SARS-CoV-2 multicomponent vaccine in healthy adults: a phase 1/2 trial

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soldierant SunSeeker Emrys

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Moderna's combo Covid and flu mRNA shot outperforms current vaccines in large trial [View all] BumRushDaShow May 7 OP

I may get this shot next fall LetMyPeopleVote May 7 #1

Hopefully this misadministration won't go beyond discouraging vaccines tanyev May 7 #2

Count on it. rubbersole May 7 #12

I've been wondering about that myself, and am more than willing to leave the country for that reason alone, Karasu May 7 #18

All of my Covid shots and boosters have been Moderna. blm May 7 #4

My oldest was in the Pfzier trial back in August of 2020. LetMyPeopleVote May 7 #5

Same here BumRushDaShow May 7 #6

lol, I knock on wood, too blm May 7 #7

I had a stuffy nose and a very low fever and tested positive LiberalArkie May 7 #10

Well I had ended up in the hospital with pneumonia BumRushDaShow May 7 #11

Oh I would have also.. I almost had to go to hospital with pneumonia years ago. That is why I am now vaxed with crap LiberalArkie May 7 #22

So have mine, knock on wood. ProudMNDemocrat May 7 #14

How? Akakoji May 7 #13

Oh brother. ShazzieB May 7 #21

I was friends with Jonas Salk Akakoji May 8 #35

I hope it gets produced past the trial. ... littlemissmartypants May 7 #3

That'll be up to the host body of the brain worm BumRushDaShow May 7 #8

Thanks so much, BRDS! ... littlemissmartypants May 7 #17

LOL BumRushDaShow May 7 #23

That's a very serious problem! 😁 🤭 littlemissmartypants May 7 #27

... BumRushDaShow May 7 #28

Snort littlemissmartypants May 7 #29

We are all being forced to participate in a herd immunity study Akakoji May 8 #36

Get it out there DENVERPOPS May 7 #9

Only problem is those anti-science dumbfucks are currently the ones running HHS. Karasu May 7 #20

Not surprised in the least Warpy May 7 #15

I'll be getting it, too... ShazzieB May 7 #19

Does this new version need new FDA approval? Lonestarblue May 7 #16

Yes BumRushDaShow May 7 #24

I wouldn't count on it coming here anytime soon with FDA Prasad and rfk jr, and potential SG Means. JohnSJ May 7 #25

THEY have the vaccine. BidenRocks May 7 #26

Sign me up ornotna May 7 #30

But Bobbers the Junkie will say you should Wolf Frankula May 7 #31

I'm in the NovaVax combo trial IbogaProject May 7 #32

All my covid vaccines have been Moderna. I've felt very good about that and hope liberalla May 8 #33

The post doesn't spell this out, but soldierant May 8 #34

Please let us know what your PCP says! SunSeeker May 8 #38

I shall. Also see BumRushDaShow comment below soldierant May 8 #45

Saw my PCP yesterday - soldierant May 15 #51

One of the points of mRNA is that it doesn't NEED eggs! BumRushDaShow May 8 #39

That' what I vaguely thought, soldierant May 8 #44

I'm a retired chemist who used to work for a HHS agency BumRushDaShow May 9 #46

Thanks! soldierant May 9 #49

There is one flu shot not make from eggs womanofthehills May 9 #48

Thanks. I'll save that information. soldierant May 9 #50

I'll be getting it for sure...if that anti-vaxx idiot RFK Jr. doesn't block it. SunSeeker May 8 #37

RFK will try to prevent its release with new testing "standards." Martin68 May 8 #40

The new FDA chief is gonna delay it. BradBo May 8 #41

Yah but will Gargles The Clown let it go through? Montauk6 May 8 #42

Good to know Hekate May 8 #43

Great I just samplegirl May 9 #47